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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK2
All Species:
13.03
Human Site:
S58
Identified Species:
26.06
UniProt:
P49760
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49760
NP_003984.2
499
60090
S58
Y
H
V
R
S
R
S
S
Y
D
D
R
S
S
D
Chimpanzee
Pan troglodytes
XP_513855
498
59985
Y58
Y
H
V
R
S
R
S
Y
D
D
R
S
S
D
R
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
S199
P
R
R
S
R
S
R
S
H
D
R
L
P
Y
Q
Dog
Lupus familis
XP_547549
536
63798
S94
Y
H
V
R
S
R
S
S
Y
D
D
R
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O35491
499
59936
S58
Y
H
V
R
S
R
S
S
Y
D
D
H
S
S
D
Rat
Rattus norvegicus
Q63117
490
58467
Q58
S
H
D
R
I
P
Y
Q
R
R
Y
R
E
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIU3
526
59419
R58
Q
S
E
S
A
H
R
R
Q
G
S
S
S
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
Y82
R
R
P
Y
D
R
H
Y
G
E
S
Y
R
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
G374
A
S
A
G
G
G
G
G
G
A
A
G
L
Q
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTF3
817
89866
H356
A
S
T
H
D
M
M
H
S
K
I
P
K
S
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
G42
A
Q
V
G
M
F
C
G
Q
E
I
G
N
I
S
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
N208
F
N
V
P
D
Q
T
N
A
I
V
P
R
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
51.2
91.5
N.A.
96.7
59.9
N.A.
N.A.
21.2
N.A.
74.9
N.A.
37
N.A.
20.4
N.A.
Protein Similarity:
100
99.8
62.3
91.7
N.A.
98.1
73.7
N.A.
N.A.
39.7
N.A.
83.8
N.A.
48.4
N.A.
34.5
N.A.
P-Site Identity:
100
60
13.3
100
N.A.
93.3
20
N.A.
N.A.
13.3
N.A.
6.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
60
20
100
N.A.
93.3
20
N.A.
N.A.
20
N.A.
13.3
N.A.
0
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
9
0
9
0
0
0
9
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
25
0
0
0
9
42
25
0
0
9
25
% D
% Glu:
0
0
9
0
0
0
0
0
0
17
0
0
9
0
0
% E
% Phe:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
9
9
9
17
17
9
0
17
0
0
0
% G
% His:
0
42
0
9
0
9
9
9
9
0
0
9
0
9
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
9
17
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
17
% L
% Met:
0
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
0
0
0
0
9
0
0
% N
% Pro:
9
0
9
9
0
9
0
0
0
0
0
17
9
0
9
% P
% Gln:
9
9
0
0
0
9
0
9
17
0
0
0
0
9
9
% Q
% Arg:
9
17
9
42
9
42
17
9
9
9
17
25
17
9
17
% R
% Ser:
9
25
0
17
34
9
34
34
9
0
17
17
42
42
9
% S
% Thr:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
9
% T
% Val:
0
0
50
0
0
0
0
0
0
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
0
9
0
0
9
17
25
0
9
9
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _